An opioid analgesic called tramadol is used to treat moderate to severe pain. By preventing pain signals from reaching the brain and changing how pain is perceived, it has an impact on the central nervous system. Tramadol reduces pain perception by binding to opioid receptors in the brain and spinal cord. Its analgesic impact is further enhanced by blocking the reuptake of norepinephrine and serotonin. Tramadol modifies the central nervous system's experience of pain by activating mu-opioid receptors. Tramadol's analgesic impact is further enhanced by its inhibition of serotonin and norepinephrine reuptake.